| Date | Location | Result | |
| Nov 05, 2021 | Lexington, Ky. | LEXINGTON CATHOLIC 33, BOURBON COUNTY 19 | Box score |
| Oct 29, 2021 | Lexington, Ky. | LEXINGTON CATHOLIC 41, SCOTT COUNTY 40 | Box score |
| Oct 22, 2021 | Lexington, Ky. | LEXINGTON CATHOLIC 50, ANDERSON COUNTY 0 | Box score |
| Oct 14, 2021 | Paris, Ky. | LEXINGTON CATHOLIC 48, BOURBON COUNTY 35 | Box score |
| Oct 08, 2021 | Danville, Ky. | BOYLE COUNTY 16, LEXINGTON CATHOLIC 10 | Box score |
| Sep 24, 2021 | Lexington, Ky. | LEXINGTON CATHOLIC 38, TATES CREEK 13 | Box score |
| Sep 17, 2021 | Lexington, Ky. | LEXINGTON CHRISTIAN 43, LEXINGTON CATHOLIC 7 | Box score |
| Sep 10, 2021 | Louisville, Ky. | LEXINGTON CATHOLIC 45, PLEASURE RIDGE PARK 30 | Box score |
| Sep 03, 2021 | Park Hills, Ky. | LEXINGTON CATHOLIC 34, COVINGTON CATHOLIC 27 | Box score |
| Aug 27, 2021 | Lexington, Ky. | LEXINGTON CATHOLIC 38, PULASKI COUNTY 36 | Box score |
| Aug 20, 2021 | Union, Ky, | LEXINGTON CATHOLIC 24, RYLE 21 | Box score |