| Date | Location | Result | |
| Nov 05, 2021 | Lexington, KY | TATES CREEK 33, HENRY CLAY 15 | Box score |
| Oct 29, 2021 | Lexington, KY | LEXINGTON CHRISTIAN 58, HENRY CLAY 0 | Box score |
| Oct 22, 2021 | LEXINGTON,KY | HENRY CLAY 34, TATES CREEK 33 | Box score |
| Oct 15, 2021 | LEXINGTON, KY | PAUL LAURENCE DUNBAR 45, HENRY CLAY 24 | Box score |
| Oct 07, 2021 | Lexington, Ky. | LAFAYETTE 35, HENRY CLAY 20 | Box score |
| Oct 01, 2021 | BSHS | BRYAN STATION 40, HENRY CLAY 22 | Box score |
| Sep 10, 2021 | Louisville, KY | EASTERN 42, HENRY CLAY 41 | Box score |
| Sep 03, 2021 | Lexington, Ky. | GREAT CROSSING 19, HENRY CLAY 13 | Box score |
| Aug 27, 2021 | Lexington, Ky. | FERN CREEK 21, HENRY CLAY 10 | Box score |
| Aug 20, 2021 | Lexington, Ky. | JOHNSON CENTRAL 60, HENRY CLAY 21 | Box score |